Created by: Atchuta Srinivas Duddu, Kishore Hari
Issue 194: This image depicts a role complexity of network topology has to play in the emergent properties of biological systems. Our recent study revealed the presence of teams of nodes, defined as groups of nodes having positive “influence” on each other and negative influence on nodes not of their groups, is a common feature of complexity across multiple networks. We linked this property of the network topology to structural and dynamical robustness of the emergent phenotypes in the context of EMP. Disrupting these teams leads to reduced stability of the epithelial and mesenchymal phenotypes, increasing the incidence of hybrid phenotypes.