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Created by: Heber Rocha, Maximilian Strobl, and Paul Macklin
Issue 320: Metastasis remains the leading cause of cancer-related mortality, driven by the complex interplay between immune cells and micrometastases. Multiscale mathematical models are invaluable tools for characterizing these tumor-immune interactions and predicting patient outcomes. In our recent study, we explored over 100,000 virtual patient trajectories, revealing three primary outcomes: uncontrolled tumor growth, partial immune control, and complete tumor elimination. This figure provides an artistic representation of the simulated tissue dynamics and key parameters influencing these outcomes. It highlights the potential and challenges of cancer patient digital twins in advancing precision oncology.