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Issue 332: The epithelial-to-mesenchymal transition (EMT), a critical step in cancer metastasis, is not a simple flip of a biological switch. Instead, cells pass through stable intermediate states that blend epithelial and mesenchymal features. We developed a mathematical model describing cell population dynamics and transition rates between EMT cell fates, and fit it directly to scRNAseq data. By modeling how cells move between states, we uncover shared intermediate state genes and provide a quantitative view of how EMT unfolds through epithelial, intermediate, and mesenchymal states.