Mathematical Oncology

Jacob Scott

Group Leader: Theory Division @ Cleveland Clinic

Cleveland, Ohio, USA
Keywords (click a keyword to view other similar labs):
theoreticalexperimentalevolutionfitness landscapestreatment resistancecollateral sensitivityevolutionary therapy.

Description: Our greatest challenge in the clinic is the emergence of resistance to our therapies, a process which is governed by Darwinian evolution. Using a suite of mathematical and experimental models, the Theory Division seeks to deconvolute the complexity of the evolutionary process into fundamental principles. We aim to use this knowledge to then curtail the evolutionary process to increase the efficacy of targeted therapies and radiation. This same knowledge can be further harnessed to understand the differences in disease progression and therapy response on a personalized basis, so that the right treatment can be given to the right patient at the right time.

Follow Jacob Scott on Twitter: @CancerConnector.

Blog posts written by Jacob Scott:

Browse the article contributions of Jacob Scott below or browse the full blog here.

Artwork by Jacob Scott:

Each week, we feature cover artwork submitted by mathematical oncology researchers around the world. Browse the contributions of Jacob Scott below. Click to expand each cover, or browse the full collection here.