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Created by: Artem Lomakin
Issue 235: When a tumour grows, mutation and selection create a mosaic of different clones. From sequencing studies, we know that such clones exist, but so far, we have not been able to see them. Here we present a method – a combination of fluorescent microscopy and mathematical modelling – that sheds light on the spatial evolution of cancer, charting the intertwined patterns of disease progression. To learn more, check out the paper here.