Jeffrey West
Group Leader: Evolutionary Dynamics, Interactions, & Therapy @ Moffitt Cancer Center
Tampa, Florida, USA
Description: The goal of our research group is to aid in targeting treatment resistance by constructing mathematical models of 1) tumor evolution and heterogeneity and 2) evolutionary-minded treatment strategies, employing techniques such as agent-based modeling, dose response convexity analysis (second-order effects), and evolutionary game theory. These methods are broadly applicable to many cancer types, but recent publications have focused on applications to breast and prostate cancer.